Multiple Lentigines Arising in Sites of Resolving Psoriatic Plaques after Treatment with Ustekinumab
نویسندگان
چکیده
منابع مشابه
Ustekinumab in the Treatment of Psoriasis and Psoriatic Arthritis
Biologics have revolutionized the therapy of the psoriatic disease spectrum. These new classes of drugs also allow deeper insight into the pathogenesis of the disease and highlight the existence of distinct "molecular" disease subgroups as evidenced by the spectrum of clinical response seen. Molecules associated with both the interleukin (IL)-17 and interferon (IFN)γ pathways have important fun...
متن کاملUstekinumab for the treatment of psoriatic arthritis: an update
Psoriatic arthritis occurs in 30% of psoriasis patients, and the treatment can be challenging in some patients. Recently, the US Food and Drug Administration approved ustekinumab, a fully human monoclonal antibody, for the management of psoriatic arthritis. In this article, we review large-scale randomized clinical trials addressing the efficacy and safety profile of ustekinumab for the treatme...
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چکیده ندارد.
15 صفحه اولS100A8/A9 in psoriatic plaques from patients with psoriatic arthritis
OBJECTIVE To evaluate levels of the calcium-binding proteins S100A8 and S100A9 in the skin of patients with psoriatic arthritis. METHODS Skin punch biopsies were obtained from patients with psoriatic arthritis and healthy control subjects. S100A8/A9 were semiquantified via immunohistochemistry and semiquantitative polymerase chain reaction. RESULTS The study included biopsies from nine pati...
متن کاملProfile of ustekinumab and its potential in the treatment of active psoriatic arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis and considered to be a less severe condition than rheumatoid arthritis. PsA patients have been treated for a long time with a number of different agents, from non-steroidal anti-inflammatory drugs to one or more disease-modifying antirheumatic drugs. In the last decade, recognition of the central role of tumor necrosis factor-alpha (...
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ژورنال
عنوان ژورنال: Annals of Dermatology
سال: 2018
ISSN: 1013-9087,2005-3894
DOI: 10.5021/ad.2018.30.3.371